(http://www.archos.com/img/archos_5it/index_5itb_1.jpg)
http://www.archos.com/products/imt/archos_5it/index.html
It runs Android, has a nice big touchscreen, $270 from Newegg. Wifi
Apps:
Squeezebox controller: http://sqcmdr.no-ip.org:9999/wiki/Documentation
SoundForm and SPLMeter: https://sites.google.com/site/bofinit/
Pandemonium: http://pandemoniumapp.com/
Tivo: http://timhoeck.com/2009/12/18/tivoremote-1-5-released/
Spectral Analyzer: http://www.radonsoft.net/
iTunes Remote Control: http://hyperfine.com/remoteforitunes/default.aspx
RadioTime: http://radiotime.com/apps/Android.aspx
PC Remote Desktop: http://softwareforme.com/
Darth Vadar Imperial March Ringtone: http://droidventures.com/
More to come, new apps are coming fast.